8/6/2023 0 Comments Pdf to epub converter 2.2.5Therefore, it is needed that we meta-analyze the clinical trials with high quality to elucidate the efficacy and safety of ascorbic acid supplementation in patients with T2DM. However, relevant studies have common problems such as the lack of large sample studies and low quality of included studies. Studies have shown that ascorbic acid supplementation can reduce blood glucose, increase insulin synthesis and secretion, improve insulin resistance, and reduce the occurrence and development of complications of type 2 diabetes mellitus (T2DM). In recent years, with the continuous improvement of people's living standards and changes in dietary structure, the incidence of diabetes is gradually increasing. ĭiabetes is one of the most common chronic diseases in the world. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The authors declare no conflicts of interest. The support institute had no role in developing the protocol. zy201602072) and the Dianjiang Science and Technology Project (No. This article was funded by the Scientific Research Project of Chongqing Health Committee (No. 2020 99:45(e23125).Įthics approval is not required for this study, because we will not analyze individual data. Ascorbic acid supplementation in type 2 diabetes mellitus: a protocol for systematic review and meta-analysis. How to cite this article: Shi L, Du X, Guo P, Huang L, Qi P, Gong Q. ∗Correspondence: Xuqin Du, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China (e-mail: ).Ībbreviations: CVD = cardiovascular disease, FBG = fasting blood glucose, HbA1c = glycosylated hemoglobin, PROSPERO = the protocol in the International Prospective Register of Systematic Reviews, RCTs = randomized controlled trials, T2DM = type 2 diabetes mellitus. AClinical Department, Dianjiang Hospital of Traditional Chinese Medicine, Dianjiang, ChongqingīCollege of Traditional Chinese Medicine, Chongqing Medical UniversityĬHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan ProvinceĭGraduate School, Hunan University of Traditional Chinese Medicine, Changsha, Hunan Province, China.
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